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Cholesterol is a type of fat that helps the human body make cell membranes, hormones, and vitamin D. The recommended total limit of cholesterol is 200mg/dL, with HDL (“good” cholesterol) being above 60mg/dL and LDL (“bad” cholesterol) being below 100mg/dL. Around 93 million American adults have a total cholesterol above the recommended total limit. Hyperlipidemia is the incidence of over-abundant lipids present in blood. This results in obstruction of arteries, since the lipids collect and stick to arterial walls. This could lead to an increased risk for heart attacks, strokes, etc.Inhibition of a gene called PCSK9 increases the removal of LDL from the bloodstream. There are currently only injectable dosage forms for PCSK9 inhibitors; the United States FDA approved drugs are alirocumab.

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