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One method for creating PDAC therapeutic interventions entailed focusing on the metabolic pathways of the tumor. Due in part to tumors’ capacity for metabolic adaptation, the efficacy and viability of these applications remain constrained. Additionally, earlier treatment initiatives to target metabolic pathways have produced serious toxicity to healthy tissue. A novel metabolic target has been found in a recent study that was published in Nature and may aid in the fight against PDAC progression. The study focuses on the metabolic pathway used for the synthesis of the amino acid ornithine. Found in meat, fish, and dairy products, ornithine plays a role in liver function and detoxification. As a critical molecule in the urea cycle, ornithine helps remove nitrogen from the body.

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